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PreservativeINS 250
E250

Sodium nitrite

What you need to know

Sodium nitrite cures bacon, ham and other processed meats. It prevents botulism — one of the most dangerous food-poisoning bacteria — and gives cured meat its pink colour.

The concern is not nitrite itself but the nitrosamines that can form from it during high-heat cooking and digestion. Nitrosamines are linked to bowel cancer, and processed meat as a category is classified as carcinogenic by IARC.

Regulators everywhere still permit it because the botulism protection is real, but the EU cut the maximum levels in 2023 and the daily intake limit is one of the smallest of any additive.

Where it stands, by region

The same additive can be approved in one country and banned in another. This is the divergence that matters most.

🇦🇺AU / NZApproved
Permitted in cured meats with maximum levels (FSANZ).
🇪🇺EURestricted
Permitted with maximum levels cut in 2023 (Reg. 2023/2108) over nitrosamine concerns.
🇺🇸USApproved
Permitted with limits; ascorbate addition required in bacon to suppress nitrosamines.
🇨🇦CAApproved
Permitted in cured meats with maximum levels.

Health evidence

How settled the science is for each area — not how dangerous. “Unknown” means not enough good studies yet.

Hyperactivity & behaviour
Unknown
Allergy & intolerance
Unknown
Gut microbiome
Unknown
Metabolic effects
Unknown
Carcinogenicity
Via nitrosamines; processed meat is IARC Group 1
Probable
Cardiovascular
Suspected

NaNO₂. ADI 0.07 mg/kg bw/day (EFSA 2017 re-evaluation). EU Regulation 2023/2108 lowered permitted levels in meat products from 2025. Key concern: endogenous nitrosamine formation.

Synthesis: SyntheticADI 0.07 mg/kg bw/day