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AntioxidantINS 319
E319

TBHQ (tert-butylhydroquinone)

What you need to know

TBHQ is a synthetic antioxidant that stops frying oils and instant-noodle oils going rancid.

It is approved everywhere with strict limits, but it attracts research attention: very high doses in animals affected the stomach lining, and some early studies have asked questions about immune effects. None of this is established at food levels.

Products that switch away from it usually use vitamin E (tocopherols) instead.

Where it stands, by region

The same additive can be approved in one country and banned in another. This is the divergence that matters most.

🇦🇺AU / NZApproved
Permitted in oils and fried products with maximum levels (FSANZ).
🇪🇺EUApproved
Permitted with maximum levels; ADI 0.7 mg/kg bw/day.
🇺🇸USApproved
Permitted (FDA).
🇨🇦CAApproved
Permitted (Health Canada).

Health evidence

How settled the science is for each area — not how dangerous. “Unknown” means not enough good studies yet.

Hyperactivity & behaviour
Unknown
Allergy & intolerance
Unknown
Gut microbiome
Unknown
Metabolic effects
Suspected
Carcinogenicity
High-dose animal evidence only
Suspected
Cardiovascular
Unknown

tert-Butylhydroquinone, a fat-soluble phenolic antioxidant. ADI 0.7 mg/kg bw/day (JECFA; EFSA 2004 concurred).

Synthesis: SyntheticADI 0.7 mg/kg bw/day