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AntioxidantINS 321
E321

BHT (butylated hydroxytoluene)

What you need to know

BHT is a synthetic antioxidant closely related to BHA, used in chewing gum, cereals and packaging fats.

Unlike BHA, the cancer agency IARC reviewed BHT and found it not classifiable as a carcinogen (Group 3). Regulators permit it with one of the lower intake limits among antioxidants.

Many manufacturers have replaced it with vitamin E in recent years.

Where it stands, by region

The same additive can be approved in one country and banned in another. This is the divergence that matters most.

🇦🇺AU / NZApproved
Permitted (FSANZ Food Standards Code).
🇪🇺EUApproved
Permitted with strict maximum levels; ADI 0.25 mg/kg bw/day (2012).
🇺🇸USApproved
Permitted (FDA).
🇨🇦CAApproved
Permitted (Health Canada).

Health evidence

How settled the science is for each area — not how dangerous. “Unknown” means not enough good studies yet.

Hyperactivity & behaviour
Unknown
Allergy & intolerance
Unknown
Gut microbiome
Unknown
Metabolic effects
Suspected
Carcinogenicity
IARC Group 3 — not classifiable
Suspected
Cardiovascular
Unknown

2,6-di-tert-butyl-4-methylphenol. ADI 0.25 mg/kg bw/day (EFSA 2012). IARC Group 3 (not classifiable).

Synthesis: SyntheticADI 0.25 mg/kg bw/day