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Acidity regulatorINS 338
E338

Phosphoric acid

What you need to know

Phosphoric acid gives colas their sharp, tangy bite and helps stop microbes growing.

High intakes of phosphate — mainly from drinking a lot of cola — have been linked in some studies to lower bone density and to enamel erosion, though overall diet matters more.

It is approved everywhere; the practical caution is regularly drinking large amounts of dark soft drinks.

Where it stands, by region

The same additive can be approved in one country and banned in another. This is the divergence that matters most.

🇦🇺AU / NZApproved
Permitted (FSANZ Food Standards Code).
🇪🇺EUApproved
Permitted; 2019 group ADI for phosphates flags high-consumer exposure.
🇺🇸USApproved
Permitted (FDA).
🇨🇦CAApproved
Permitted (Health Canada).

Health evidence

How settled the science is for each area — not how dangerous. “Unknown” means not enough good studies yet.

Hyperactivity & behaviour
Unknown
Allergy & intolerance
Unknown
Gut microbiome
Unknown
Metabolic effects
Bone density in very high cola intake
Suspected
Carcinogenicity
Unknown
Cardiovascular
Suspected

H₃PO₄. EFSA set a group ADI for phosphates of 40 mg/kg bw/day (as phosphorus) in 2019, noting high consumers can exceed it.

Synthesis: Synthetic (mineral-derived)ADI 40 mg/kg bw/day (group, as P)