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Flavour enhancerINS 631
E631

Disodium inosinate

What you need to know

Disodium inosinate is an umami booster paired with MSG in savoury snacks and instant noodles.

It occurs naturally in meat and fish.

Regulators consider it low concern.

Where it stands, by region

The same additive can be approved in one country and banned in another. This is the divergence that matters most.

🇦🇺AU / NZApproved
Permitted (FSANZ Food Standards Code).
🇪🇺EUApproved
Permitted (EFSA).
🇺🇸USApproved
Permitted (FDA).
🇨🇦CAApproved
Permitted (Health Canada).

Health evidence

How settled the science is for each area — not how dangerous. “Unknown” means not enough good studies yet.

Hyperactivity & behaviour
Unknown
Allergy & intolerance
Suspected
Gut microbiome
Unknown
Metabolic effects
Unknown
Carcinogenicity
Unknown
Cardiovascular
Unknown

Disodium salt of inosine 5′-monophosphate. JECFA ADI 'not specified'.

Synthesis: Fermentation-derivedADI Not specified (acceptable)