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SweetenerINS 951Sources conflict
E951

Aspartame

What you need to know

Aspartame is an intense sweetener, about 200 times sweeter than sugar. It lets drinks taste sweet with almost no calories.

In 2023 two expert groups looked at the same evidence and reached different-sounding conclusions. The cancer-research agency IARC classified it as “possibly carcinogenic” (Group 2B). The food-safety committee JECFA reviewed the same studies and kept its acceptable daily intake unchanged.

What both agree on: at normal consumption levels there is no proven harm for the general public. People with the rare condition PKU must avoid it because it contains phenylalanine.

Where it stands, by region

The same additive can be approved in one country and banned in another. This is the divergence that matters most.

🇦🇺AU / NZApproved
Permitted; PKU advisory statement required (“contains phenylalanine”).
🇪🇺EUApproved
Permitted; PKU advisory required. ADI reaffirmed 2013.
🇺🇸USApproved
Permitted; PKU advisory required. FDA reaffirmed safety 2023.
🇨🇦CAApproved
Permitted; PKU advisory required.

Health evidence

How settled the science is for each area — not how dangerous. “Unknown” means not enough good studies yet.

Hyperactivity & behaviour
Unknown
Allergy & intolerance
Unknown
Gut microbiome
Suspected
Metabolic effects
Suspected
Carcinogenicity
Sources conflict (IARC 2B vs JECFA)
Suspected
Cardiovascular
Unknown

Chemical name: methyl L-α-aspartyl-L-phenylalaninate. A methyl ester of a dipeptide. Acceptable Daily Intake 40 mg/kg body weight per day (EFSA, 2013); FDA sets 50 mg/kg.

Synthesis: Synthetic (dipeptide)ADI 40 mg/kg bw/day